| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GP9 |
| Gene ID: | 2815 |
| Uniprot ID: | GPIX_HUMAN |
| Immunogen Region: | 17-140 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 17-140 of human CD42a (NP_000165.1). |
| Immunogen Sequence: | TKDCPSPCTCRALETMGLWV DCRGHGLTALPALPARTRHL LLANNSLQSVPPGAFDHLPQ LQTLDVTQNPWHCDCSLTYL RLWLEDRTPEALLQVRCASP SLAAHGPLGRLTGYQLGSCG WQLQ |
| Function | The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib. |
| Protein Name | Platelet Glycoprotein IxGp-IxGpixGlycoprotein 9Cd Antigen Cd42a |
| Database Links | Reactome: R-HSA-140837Reactome: R-HSA-430116Reactome: R-HSA-75892Reactome: R-HSA-76009Reactome: R-HSA-9673221Reactome: R-HSA-9845620Reactome: R-HSA-9846298 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Platelet Glycoprotein Ix antibodyAnti-Gp-Ix antibodyAnti-Gpix antibodyAnti-Glycoprotein 9 antibodyAnti-Cd Antigen Cd42a antibodyAnti-GP9 antibody |
Information sourced from Uniprot.org
