Anti-GP9 antibody (17-140) (STJ11104761)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal Platelet Glycoprotein Ix (17-140) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GP9 |
| Gene ID | 2815 |
| Uniprot ID | GPIX_HUMAN |
| Immunogen Region | 17-140 |
| Immunogen Sequence | TKDCPSPCTCRALETMGLWV DCRGHGLTALPALPARTRHL LLANNSLQSVPPGAFDHLPQ LQTLDVTQNPWHCDCSLTYL RLWLEDRTPEALLQVRCASP SLAAHGPLGRLTGYQLGSCG WQLQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 17-140 of human CD42a (NP_000165.1). |
Additional Info
| Function | The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib. |
| Protein Name | Platelet Glycoprotein IxGp-IxGpixGlycoprotein 9Cd Antigen Cd42a |
| Database Links | Reactome: R-HSA-140837Reactome: R-HSA-430116Reactome: R-HSA-75892Reactome: R-HSA-76009Reactome: R-HSA-9673221Reactome: R-HSA-9845620Reactome: R-HSA-9846298 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Platelet Glycoprotein Ix antibodyAnti-Gp-Ix antibodyAnti-Gpix antibodyAnti-Glycoprotein 9 antibodyAnti-Cd Antigen Cd42a antibodyAnti-GP9 antibody |
Information sourced from Uniprot.org