Anti-GNPTG antibody (216-266 aa) (STJ197795)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human GNPTG at the amino acid range 216-266
General Information
| Short Description | Rabbit polyclonal anti-N-acetylglucosamine-1-phosphotransferase subunit gamma (216-266 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GNPTG |
| Gene ID | 84572 |
| Uniprot ID | GNPTG_HUMAN |
| Immunogen | Synthesized peptide derived from the human GNPTG at the amino acid range 216-266 |
| Immunogen Region | 216-266 aa |
| Specificity | This antibody detects endogenous levels of human GNPTG |
Additional Info
| Post Translational Modifications | Cys-245 mediates the formation of the interchain disulfide bond for formation of the homodimer. Cys-142, Cys-157 and Cys-169 are involved in intramolecular disulfide bonds formation. |
| Function | Non-catalytic subunit of the N-acetylglucosamine-1-phosphotransferase complex, an enzyme that catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. Binds and presents the high mannose glycans of the acceptor to the catalytic alpha and beta subunits (GNPTAB). Enhances the rate of N-acetylglucosamine-1-phosphate transfer to the oligosaccharides of acid hydrolase acceptors. |
| Protein Name | N-Acetylglucosamine-1-Phosphotransferase Subunit GammaGlcnac-1-Phosphotransferase Subunit GammaUdp-N-Acetylglucosamine-1-Phosphotransferase Subunit Gamma |
| Database Links | |
| Cellular Localisation | SecretedGolgi Apparatus |
| Alternative Antibody Names | Anti-N-Acetylglucosamine-1-Phosphotransferase Subunit Gamma antibodyAnti-Glcnac-1-Phosphotransferase Subunit Gamma antibodyAnti-Udp-N-Acetylglucosamine-1-Phosphotransferase Subunit Gamma antibodyAnti-GNPTG antibodyAnti-C16orf27 antibodyAnti-GNPTAG antibodyAnti-CAB56184 antibodyAnti-LP2537 antibody |
Information sourced from Uniprot.org