Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-N-acetylglucosamine-1-phosphotransferase subunit gamma (216-266 aa) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:1000-2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | GNPTG |
Gene ID: | 84572 |
Uniprot ID: | GNPTG_HUMAN |
Immunogen Region: | 216-266 aa |
Specificity: | This antibody detects endogenous levels of human GNPTG |
Immunogen: | Synthesized peptide derived from the human GNPTG at the amino acid range 216-266 |
Post Translational Modifications | Cys-245 mediates the formation of the interchain disulfide bond for formation of the homodimer. Cys-142, Cys-157 and Cys-169 are involved in intramolecular disulfide bonds formation. |
Function | Non-catalytic subunit of the N-acetylglucosamine-1-phosphotransferase complex, an enzyme that catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. Binds and presents the high mannose glycans of the acceptor to the catalytic alpha and beta subunits (GNPTAB). Enhances the rate of N-acetylglucosamine-1-phosphate transfer to the oligosaccharides of acid hydrolase acceptors. |
Protein Name | N-Acetylglucosamine-1-Phosphotransferase Subunit Gamma Glcnac-1-Phosphotransferase Subunit Gamma Udp-N-Acetylglucosamine-1-Phosphotransferase Subunit Gamma |
Cellular Localisation | Secreted Golgi Apparatus |
Alternative Antibody Names | Anti-N-Acetylglucosamine-1-Phosphotransferase Subunit Gamma antibody Anti-Glcnac-1-Phosphotransferase Subunit Gamma antibody Anti-Udp-N-Acetylglucosamine-1-Phosphotransferase Subunit Gamma antibody Anti-GNPTG antibody Anti-C16orf27 antibody Anti-GNPTAG antibody Anti-CAB56184 antibody Anti-LP2537 antibody |
Information sourced from Uniprot.org