• The 2 NA-O-methylguanosine (Gm) Rabbit monoclonal antibody (STJ11104063) are tested in Dot Blot against 2 NA-O-methylguanosine and unmodified guanosine. 2 NA-O-methylguanosine:Biotin-5 NA GCATAATGACTACT (Gm) 3 NA unmodified guanosine:Biotin-5 NA GCATAATGACTACTG3 NA

Anti-Gm antibody [S4063RM] (STJ11104063)

SKU:
STJ11104063

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Host: Rabbit
Reactivity: Species independent
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Gm is suitable for use in research applications.
Clonality: Monoclonal
Clone ID: S4063RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: DB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunogen: Gm
Immunogen Sequence: Gm conjugated to KLH
Background RNA methylation plays a significant regulatory role in various of physiological activities and it has gradually become a hotspot of epigenetics in the past decade. 2 NA-O-methyladenosine (Am) , 2 NA-O-methylguanosine (Gm) , 2 NA-O-methylcytidine (Cm) , 2 NA-O-methyluridine (Um) , N 6-methyladenosine (m6A) , N 1-methylguanosine (m1G) , 5-methylcytidine (m5C) , and 5-methyluridine (m5U) are representative 2 NA-O-methylation and base-methylation modified epigenetic marks of RNA. 2 NA-O-methyltransferase is a modified nucleoside that is produced in tRNAs by the action of tRNA guanosine-2 NA-O-methyltransferase, using S-adenosyl-L-methionine as a substrate. Through its interaction with other modified nucleosides, 2 NA-O-methylguanosine is thought to stabilize the structure of the tRNA.

Information sourced from Uniprot.org

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