| Host: | Rabbit |
| Applications: | WB/IF/ICC/IP/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:100IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GLDC |
| Gene ID: | 2731 |
| Uniprot ID: | GCSP_HUMAN |
| Immunogen Region: | 36-290 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 36-290 of human GLDC (NP_000161.2). |
| Immunogen Sequence: | DSSSGGGDSAAAGASRLLER LLPRHDDFARRHIGPGDKDQ REMLQTLGLASIDELIEKTV PANIRLKRPLKMEDPVCENE ILATLHAISSKNQIWRSYIG MGYYNCSVPQTILRNLLENS GWITQYTPYQPEVSQGRLES LLNYQTMVCDITGLDMANAS LLDEGTAAAEALQLCYRHNK RRKFLVDPRCHPQTIAVVQT RAKYTGVLTELKLPCEMDFS GKDVSGVLFQYPDTEGKVE |
| Function | The glycine cleavage system catalyzes the degradation of glycine. The P protein (GLDC) binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor.CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (GCSH). |
| Protein Name | Glycine DehydrogenaseDecarboxylating - MitochondrialGlycine Cleavage System P ProteinGlycine DecarboxylaseGlycine DehydrogenaseAminomethyl-Transferring |
| Database Links | Reactome: R-HSA-6783984 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Glycine Dehydrogenase antibodyAnti-Decarboxylating - Mitochondrial antibodyAnti-Glycine Cleavage System P Protein antibodyAnti-Glycine Decarboxylase antibodyAnti-Glycine Dehydrogenase antibodyAnti-Aminomethyl-Transferring antibodyAnti-GLDC antibodyAnti-GCSP antibody |
Information sourced from Uniprot.org