Anti-GGA1 antibody (280-330 aa) (STJ13101194)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 280-330 of mouse GGA1 conjugated to blue carrier protein was used as the antigen. The peptide shares 95% identity with human sequence.
General Information
| Short Description | Rabbit polyclonal anti-GGA1 (280-330 aa) for use in IHC and WB in Mouse and Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Mouse/Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | Gga1 |
| Gene ID | 106039 |
| Uniprot ID | GGA1_MOUSE |
| Immunogen | A synthetic peptide from aa region 280-330 of mouse GGA1 conjugated to blue carrier protein was used as the antigen. The peptide shares 95% identity with human sequence. |
| Immunogen Region | 280-330 aa |
| Specificity | Specific for GGA1. |
Additional Info
| Function | Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (DXXLL) motif. Mediates export of the GPCR receptor ADRA2B to the cell surface. Required for targeting PKD1:PKD2 complex from the trans-Golgi network to the cilium membrane. Regulates retrograde transport of proteins such as phosphorylated form of BACE1 from endosomes to the trans-Golgi network. |
| Protein Name | Adp-Ribosylation Factor-Binding Protein Gga1Gamma-Adaptin-Related Protein 1Golgi-Localized - Gamma Ear-Containing - Arf-Binding Protein 1 |
| Database Links | |
| Cellular Localisation | Golgi ApparatusTrans-Golgi Network MembranePeripheral Membrane ProteinEndosome MembraneEarly Endosome Membrane |
| Alternative Antibody Names | Anti-Adp-Ribosylation Factor-Binding Protein Gga1 antibodyAnti-Gamma-Adaptin-Related Protein 1 antibodyAnti-Golgi-Localized - Gamma Ear-Containing - Arf-Binding Protein 1 antibodyAnti-Gga1 antibody |
Information sourced from Uniprot.org