Anti-GFAP antibody (350-432) (STJ116876)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GFAP (350-432) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GFAP |
| Gene ID | 2670 |
| Uniprot ID | GFAP_HUMAN |
| Immunogen Region | 350-432 |
| Immunogen Sequence | QDLLNVKLALDIEIATYRKL LEGEENRITIPVQTFSNLQI RETSLDTKSVSEGHLKRNIV VKTVEMRDGEVIKESKQEHK DVM |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 350-432 of human GFAP (NP_002046.1). |
Additional Info
| Tissue Specificity | Expressed in cells lacking fibronectin. |
| Post Translational Modifications | Phosphorylated by PKN1. |
| Function | GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. |
| Protein Name | Glial Fibrillary Acidic ProteinGfap |
| Database Links | Reactome: R-HSA-1251985Reactome: R-HSA-9613829 |
| Cellular Localisation | CytoplasmAssociated With Intermediate Filaments |
| Alternative Antibody Names | Anti-Glial Fibrillary Acidic Protein antibodyAnti-Gfap antibodyAnti-GFAP antibody |
Information sourced from Uniprot.org