• Western blot analysis of extracts of various cell lines, using GEM antibody (STJ29569) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-GEM antibody (1-150) (STJ29569)

SKU:
STJ29569

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-GEM (1-150) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GEM
Gene ID: 2669
Uniprot ID: GEM_HUMAN
Immunogen Region: 1-150
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human GEM (NP_005252.1).
Immunogen Sequence: MTLNNVTMRQGTVGMQPQQQ RWSIPADGRHLMVQKEPHQY SHRNRHSATPEDHCRRSWSS DSTDSVISSESGNTYYRVVL IGEQGVGKSTLANIFAGVHD SMDSDCEVLGEDTYERTLMV DGESATIILLDMWENKGENE WLHDHCMQVG
Tissue Specificity Most abundant in thymus, spleen, kidney, lung, and testis. Less abundant in heart, brain, liver and skeletal muscle.
Post Translational Modifications Phosphorylated on tyrosine residues.
Function Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity.
Protein Name Gtp-Binding Protein Gem
Gtp-Binding Mitogen-Induced T-Cell Protein
Ras-Like Protein Kir
Database Links Reactome: R-HSA-9768919
Cellular Localisation Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Alternative Antibody Names Anti-Gtp-Binding Protein Gem antibody
Anti-Gtp-Binding Mitogen-Induced T-Cell Protein antibody
Anti-Ras-Like Protein Kir antibody
Anti-GEM antibody
Anti-KIR antibody

Information sourced from Uniprot.org

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