Anti-GEM antibody (1-150) (STJ29569)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ29569
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General Information

Short DescriptionRabbit polyclonal GEM (1-150) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolGEM
Gene ID2669
Uniprot IDGEM_HUMAN
Immunogen Region1-150
Immunogen SequenceMTLNNVTMRQGTVGMQPQQQ RWSIPADGRHLMVQKEPHQY SHRNRHSATPEDHCRRSWSS DSTDSVISSESGNTYYRVVL IGEQGVGKSTLANIFAGVHD SMDSDCEVLGEDTYERTLMV DGESATIILLDMWENKGENE WLHDHCMQVG
SpecificityRecombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human GEM (NP_005252.1).

Additional Info

Tissue Specificity Most abundant in thymus, spleen, kidney, lung, and testis. Less abundant in heart, brain, liver and skeletal muscle.
Post Translational Modifications Phosphorylated on tyrosine residues.
Function Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity.
Protein Name Gtp-Binding Protein Gem
Gtp-Binding Mitogen-Induced T-Cell Protein
Ras-Like Protein Kir
Database Links Reactome: R-HSA-9768919
Cellular Localisation Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Alternative Antibody Names Anti-Gtp-Binding Protein Gem antibody
Anti-Gtp-Binding Mitogen-Induced T-Cell Protein antibody
Anti-Ras-Like Protein Kir antibody
Anti-GEM antibody
Anti-KIR antibody

Information sourced from Uniprot.org

Citations

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