| Short Description : | Rabbit polyclonal GEM (1-150) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GEM |
| Gene ID: | 2669 |
| Uniprot ID: | GEM_HUMAN |
| Immunogen Region: | 1-150 |
| Immunogen Sequence: | MTLNNVTMRQGTVGMQPQQQ RWSIPADGRHLMVQKEPHQY SHRNRHSATPEDHCRRSWSS DSTDSVISSESGNTYYRVVL IGEQGVGKSTLANIFAGVHD SMDSDCEVLGEDTYERTLMV DGESATIILLDMWENKGENE WLHDHCMQVG |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human GEM (NP_005252.1). |
| Tissue Specificity | Most abundant in thymus, spleen, kidney, lung, and testis. Less abundant in heart, brain, liver and skeletal muscle. |
| Post Translational Modifications | Phosphorylated on tyrosine residues. |
| Function | Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. |
| Protein Name | Gtp-Binding Protein GemGtp-Binding Mitogen-Induced T-Cell ProteinRas-Like Protein Kir |
| Database Links | Reactome: R-HSA-9768919 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Gtp-Binding Protein Gem antibodyAnti-Gtp-Binding Mitogen-Induced T-Cell Protein antibodyAnti-Ras-Like Protein Kir antibodyAnti-GEM antibodyAnti-KIR antibody |
Information sourced from Uniprot.org
