| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GCM1 (207-436) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:100 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GCM1 |
| Gene ID: |
8521 |
| Uniprot ID: |
GCM1_HUMAN |
| Immunogen Region: |
207-436 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 207-436 of human GCM1 (NP_003634.2). |
| Immunogen Sequence: |
SFQEGVQLPGSYSGHLIANT PQQNSLNDCFSFSKSYGLGG ITDLTDQTSTVDPMKLYEKR KLSSSRTYSSGDLLPPSASG VYSDHGDLQAWSKNAALGRN HLADNCYSNYPFPLTSWPCS FSPSQNSSEPFYQQLPLEPP AAKTGCPPLWPNPAGNLYEE KVHVDFNSYVQSPAYHSPQE DPFLFTYASHPHQQYSLPSK SSKWDFEEEMTYLGLDHCNN DMLLNLCPLR |
| Tissue Specificity | Highly expressed in the placenta. Expressed in trophoblast cells of the villi. |
| Post Translational Modifications | Polyubiquitinated in the presence of UBE2D2 and FBXW2 (in vitro). |
| Function | Transcription factor involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer. Binds to the SYDE1 promoter. Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development. |
| Protein Name | Chorion-Specific Transcription Factor GcmaHgcmaGcm Motif Protein 1Glial Cells Missing Homolog 1 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Chorion-Specific Transcription Factor Gcma antibodyAnti-Hgcma antibodyAnti-Gcm Motif Protein 1 antibodyAnti-Glial Cells Missing Homolog 1 antibodyAnti-GCM1 antibodyAnti-GCMA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
