Anti-GCM1 antibody (207-436) (STJ29421)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GCM1 (207-436) antibody for use in WB, IF, ICC and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GCM1 |
| Gene ID | 8521 |
| Uniprot ID | GCM1_HUMAN |
| Immunogen Region | 207-436 |
| Immunogen Sequence | SFQEGVQLPGSYSGHLIANT PQQNSLNDCFSFSKSYGLGG ITDLTDQTSTVDPMKLYEKR KLSSSRTYSSGDLLPPSASG VYSDHGDLQAWSKNAALGRN HLADNCYSNYPFPLTSWPCS FSPSQNSSEPFYQQLPLEPP AAKTGCPPLWPNPAGNLYEE KVHVDFNSYVQSPAYHSPQE DPFLFTYASHPHQQYSLPSK SSKWDFEEEMTYLGLDHCNN DMLLNLCPLR |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 207-436 of human GCM1 (NP_003634.2). |
Additional Info
| Tissue Specificity | Highly expressed in the placenta. Expressed in trophoblast cells of the villi. |
| Post Translational Modifications | Polyubiquitinated in the presence of UBE2D2 and FBXW2 (in vitro). |
| Function | Transcription factor involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer. Binds to the SYDE1 promoter. Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development. |
| Protein Name | Chorion-Specific Transcription Factor GcmaHgcmaGcm Motif Protein 1Glial Cells Missing Homolog 1 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Chorion-Specific Transcription Factor Gcma antibodyAnti-Hgcma antibodyAnti-Gcm Motif Protein 1 antibodyAnti-Glial Cells Missing Homolog 1 antibodyAnti-GCM1 antibodyAnti-GCMA antibody |
Information sourced from Uniprot.org