• Western blot analysis of lysates from COLO205 cells, using GLR Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of COLO205 cells using Glucagon Receptor Polyclonal Antibody
  • Immunofluorescence analysis of HeLa cells, using GLR Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using Glucagon Receptor Polyclonal Antibody

Anti-GCGR antibody (95-144 aa) (STJ93282)

SKU:
STJ93282

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Glucagon receptor (95-144 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GCGR
Gene ID: 2642
Uniprot ID: GLR_HUMAN
Immunogen Region: 95-144 aa
Specificity: Glucagon Receptor Polyclonal Antibody detects endogenous levels of Glucagon Receptor protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human GLR at the amino acid range 95-144
Function G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
Protein Name Glucagon Receptor
Gl-R
Database Links Reactome: R-HSA-163359
Reactome: R-HSA-416476
Reactome: R-HSA-418555
Reactome: R-HSA-420092
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Is Rapidly Internalized After Ligand-Binding
Alternative Antibody Names Anti-Glucagon Receptor antibody
Anti-Gl-R antibody
Anti-GCGR antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance