| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GCDH (149-438) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GCDH |
| Gene ID: |
2639 |
| Uniprot ID: |
GCDH_HUMAN |
| Immunogen Region: |
149-438 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 149-438 of human GCDH (NP_000150.1). |
| Immunogen Sequence: |
MHPIYAYGSEEQRQKYLPQL AKGELLGCFGLTEPNSGSDP SSMETRAHYNSSNKSYTLNG TKTWITNSPMADLFVVWARC EDGCIRGFLLEKGMRGLSAP RIQGKFSLRASATGMIIMDG VEVPEENVLPGASSLGGPFG CLNNARYGIAWGVLGASEFC LHTARQYALDRMQFGVPLAR NQLIQKKLADMLTEITLGLH ACLQLGRLKDQDKAAPEMVS LLKRNNCGKALDIARQARD |
| Tissue Specificity | Isoform Long and isoform Short are expressed in fibroblasts and liver. |
| Function | Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive. |
| Protein Name | Glutaryl-Coa Dehydrogenase - MitochondrialGcd |
| Database Links | Reactome: R-HSA-71064 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Glutaryl-Coa Dehydrogenase - Mitochondrial antibodyAnti-Gcd antibodyAnti-GCDH antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
