Anti-GATAD2B antibody (STJA0008240)

SKU:
STJA0008240

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Transcriptional repressor p66-beta is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GATAD2B
Gene ID: 57459
Uniprot ID: P66B_HUMAN
Specificity: This antibody detects endogenous levels of GATAD2B at Human, Mouse
Immunogen: Synthesized peptide derived from human GATAD2B
Function Transcriptional repressor. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2A. Targets MBD3 to discrete loci in the nucleus. May play a role in synapse development.
Protein Name Transcriptional Repressor P66-Beta
Gata Zinc Finger Domain-Containing Protein 2b
P66/P68
Database Links Reactome: R-HSA-3214815
Reactome: R-HSA-427389
Reactome: R-HSA-6804758
Reactome: R-HSA-73762
Reactome: R-HSA-8943724
Reactome: R-HSA-9679191
Cellular Localisation Nucleus Speckle
Nucleus
Chromosome
Speckled Nuclear Localization Requires Both Cr1 And Cr2 Regions
Localizes To Sites Of Dna Damage
Alternative Antibody Names Anti-Transcriptional Repressor P66-Beta antibody
Anti-Gata Zinc Finger Domain-Containing Protein 2b antibody
Anti-P66/P68 antibody
Anti-GATAD2B antibody
Anti-KIAA1150 antibody

Information sourced from Uniprot.org

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