| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Transcriptional repressor p66-beta is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GATAD2B |
| Gene ID: |
57459 |
| Uniprot ID: |
P66B_HUMAN |
| Specificity: |
This antibody detects endogenous levels of GATAD2B at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human GATAD2B |
| Function | Transcriptional repressor. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2A. Targets MBD3 to discrete loci in the nucleus. May play a role in synapse development. |
| Protein Name | Transcriptional Repressor P66-BetaGata Zinc Finger Domain-Containing Protein 2bP66/P68 |
| Database Links | Reactome: R-HSA-3214815Reactome: R-HSA-427389Reactome: R-HSA-6804758Reactome: R-HSA-73762Reactome: R-HSA-8943724Reactome: R-HSA-9679191 |
| Cellular Localisation | Nucleus SpeckleNucleusChromosomeSpeckled Nuclear Localization Requires Both Cr1 And Cr2 RegionsLocalizes To Sites Of Dna Damage |
| Alternative Antibody Names | Anti-Transcriptional Repressor P66-Beta antibodyAnti-Gata Zinc Finger Domain-Containing Protein 2b antibodyAnti-P66/P68 antibodyAnti-GATAD2B antibodyAnti-KIAA1150 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
