Anti-GATAD2B antibody (STJA0008240)

SKU:
STJA0008240
€58.80 - €313.20
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Short Description :Rabbit polyclonal anti-Transcriptional repressor p66-beta for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:GATAD2B
Gene ID:57459
Uniprot ID:P66B_HUMAN
Immunogen:Synthesized peptide derived from human GATAD2B
Specificity:This antibody detects endogenous levels of GATAD2B at Human, Mouse
Function Transcriptional repressor. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2A. Targets MBD3 to discrete loci in the nucleus. May play a role in synapse development.
Protein Name Transcriptional Repressor P66-Beta
Gata Zinc Finger Domain-Containing Protein 2b
P66/P68
Database Links Reactome: R-HSA-3214815
Reactome: R-HSA-427389
Reactome: R-HSA-6804758
Reactome: R-HSA-73762
Reactome: R-HSA-8943724
Reactome: R-HSA-9679191
Reactome: R-HSA-9843940
Reactome: R-HSA-9844594
Reactome: R-HSA-9845323
Cellular Localisation Nucleus Speckle
Nucleus
Chromosome
Speckled Nuclear Localization Requires Both Cr1 And Cr2 Regions
Localizes To Sites Of Dna Damage
Alternative Antibody Names Anti-Transcriptional Repressor P66-Beta antibody
Anti-Gata Zinc Finger Domain-Containing Protein 2b antibody
Anti-P66/P68 antibody
Anti-GATAD2B antibody
Anti-KIAA1150 antibody

Information sourced from Uniprot.org