Anti-GAK antibody (101-150 aa) (STJ93199)

Name: Anti-GAK antibody (101-150 aa) (STJ93199)
SKU: STJ93199
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

ImmunogenThe antiserum was produced against synthesized peptide derived from the human GAK at the amino acid range 101-150

STJ93199

Current Stock:

🚚 Free UK Delivery on orders over £150

Quantity:

Processing The item has been added

Enquire For Bulk Order

✓ 1-Year Performance Guarantee | SDS & Datasheet Included | Expert Tech Support | Covered by St John's Laboratory Guarantee

Short Description	Rabbit polyclonal anti-Cyclin-G-associated kinase (101-150 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC/IF/ELISA
Host	Rabbit
Reactivity	Human/Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	1 mg/mL
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range	WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:5000
Formulation	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	GAK
Gene ID	2580
Uniprot ID	GAK_HUMAN
Immunogen	The antiserum was produced against synthesized peptide derived from the human GAK at the amino acid range 101-150
Immunogen Region	101-150 aa
Specificity	GAK Polyclonal Antibody detects endogenous levels of GAK protein.

Function	Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. May play a role in clathrin-mediated endocytosis and intracellular trafficking, and in the dynamics of clathrin assembly/disassembly.
Protein Name	Cyclin-G-Associated Kinase Dnaj Homolog Subfamily C Member 26
Database Links	Reactome: R-HSA-432722 Reactome: R-HSA-8856828
Cellular Localisation	Cytoplasm Perinuclear Region Golgi Apparatus Trans-Golgi Network Cell Junction Focal Adhesion Cytoplasmic Vesicle Clathrin-Coated Vesicle Localizes To The Perinuclear Area And To The Trans-Golgi Network Also Seen On The Plasma Membrane Probably At Focal Adhesions Recruitment To Clathrin-Coated Vesicles Depends On Temporal Variations In Phosphoinositide Composition Of Clathrin-Coated Vesicles
Alternative Antibody Names	Anti-Cyclin-G-Associated Kinase antibody Anti-Dnaj Homolog Subfamily C Member 26 antibody Anti-GAK antibody Anti-DNAJC26 antibody

Information sourced from Uniprot.org