Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Cyclin-G-associated kinase (101-150 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:5000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
GAK |
Gene ID: |
2580 |
Uniprot ID: |
GAK_HUMAN |
Immunogen Region: |
101-150 aa |
Specificity: |
GAK Polyclonal Antibody detects endogenous levels of GAK protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human GAK at the amino acid range 101-150 |
Function | Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. |
Protein Name | Cyclin-G-Associated Kinase |
Database Links | Reactome: R-HSA-432722Reactome: R-HSA-8856828 |
Cellular Localisation | CytoplasmPerinuclear RegionGolgi ApparatusTrans-Golgi NetworkCell JunctionFocal AdhesionLocalizes To The Perinuclear Area And To The Trans-Golgi NetworkAlso Seen On The Plasma MembraneProbably At Focal Adhesions |
Alternative Antibody Names | Anti-Cyclin-G-Associated Kinase antibodyAnti-GAK antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance