Anti-GAD2 antibody (401-585) (STJ23739)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GAD2 (401-585) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GAD2 |
| Gene ID | 2572 |
| Uniprot ID | DCE2_HUMAN |
| Immunogen Region | 401-585 |
| Immunogen Sequence | PLQCSALLVREEGLMQNCNQ MHASYLFQQDKHYDLSYDTG DKALQCGRHVDVFKLWLMWR AKGTTGFEAHVDKCLELAEY LYNIIKNREGYEMVFDGKPQ HTNVCFWYIPPSLRTLEDNE ERMSRLSKVAPVIKARMMEY GTTMVSYQPLGDKVNFFRMV ISNPAATHQDIDFLIEEIER LGQDL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 401-585 of human GAD65/GAD2 (NP_001127838.1). |
Additional Info
| Post Translational Modifications | Phosphorylated.which does not affect kinetic parameters or subcellular location. Palmitoylated.which is required for presynaptic clustering. |
| Function | Catalyzes the production of GABA. |
| Protein Name | Glutamate Decarboxylase 265 Kda Glutamic Acid DecarboxylaseGad-65Glutamate Decarboxylase 65 Kda Isoform |
| Database Links | Reactome: R-HSA-888568Reactome: R-HSA-888590Reactome: R-HSA-9022927 |
| Cellular Localisation | CytoplasmCytosolCytoplasmic VesiclePresynaptic Cell MembraneLipid-AnchorGolgi Apparatus MembranePeripheral Membrane ProteinCytoplasmic SideAssociated To Cytoplasmic VesiclesIn NeuronsCytosolic Leaflet Of Golgi Membranes And Presynaptic Clusters |
| Alternative Antibody Names | Anti-Glutamate Decarboxylase 2 antibodyAnti-65 Kda Glutamic Acid Decarboxylase antibodyAnti-Gad-65 antibodyAnti-Glutamate Decarboxylase 65 Kda Isoform antibodyAnti-GAD2 antibodyAnti-GAD65 antibody |
Information sourced from Uniprot.org