• Western blot of mouse brain lysates from wild type (WT) and Alpha 3-knockout (K/O) animals showing specific immunolabeling of the ~51 kDa Alpha 3-subunit of the GABAA-R. The labeling was absent from a lysate prepared from Alpha 3-knockout animals.
  • Immunostaining of rat amygdala showing labeling of GABAA Alpha 3 subunit (DAB, 1:100).

Anti-GABRA3 antibody (N-Term) (STJA0003642)

SKU:
STJA0003642-100

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Host: Rabbit
Applications: WB/IHC
Reactivity: Mouse/Rat/Bovine/Canine/Human/Non-Human Primates/Zebrafish
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-GABAA Receptor a 3 (N-Term) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol.
Purification: This antibody was antigen affinity purified from serum.
Dilution Range: WB 1:1000
IHC 1:100
ICC
IP
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: Gabra3
Gene ID: 24947
Uniprot ID: GBRA3_RAT
Immunogen Region: N-Term
Immunogen: Synthetic peptide from the N-terminal region of the alpha 3 subunit.
Tissue Specificity Expressed in most brain regions.
Function GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Protein Name Gamma-Aminobutyric Acid Receptor Subunit Alpha-3
Gaba(A Receptor Subunit Alpha-3
Database Links Reactome: R-RNO-977443
Cellular Localisation Postsynaptic Cell Membrane
Multi-Pass Membrane Protein
Cell Membrane
Alternative Antibody Names Anti-Gamma-Aminobutyric Acid Receptor Subunit Alpha-3 antibody
Anti-Gaba(A Receptor Subunit Alpha-3 antibody
Anti-Gabra3 antibody
Anti-Gabra-3 antibody

Information sourced from Uniprot.org

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