| Post Translational Modifications | O-glycosylated.required for stabilization and translocation to the plasma membrane. |
| Function | Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Reduces the apparent affinity for external K(+), an effect that depends on the presence of external Na(+) and voltage. Increases the apparent affinity for intracellular Na(+). |
| Protein Name | Fxyd Domain-Containing Ion Transport Regulator 7 |
| Database Links | Reactome: R-HSA-5578775Reactome: R-HSA-936837Reactome: R-HSA-9679191 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinAble To Translocate To The Plasma Membrane Independent Of Its Association With Nka (In Vitro) |
| Alternative Antibody Names | Anti-Fxyd Domain-Containing Ion Transport Regulator 7 antibodyAnti-FXYD7 antibody |
Information sourced from Uniprot.org