Anti-FXYD7 antibody (1-80) (STJ117095)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal FXYD7 (1-80) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FXYD7 |
| Gene ID | 53822 |
| Uniprot ID | FXYD7_HUMAN |
| Immunogen Region | 1-80 |
| Immunogen Sequence | MATPTQTPTKAPEEPDPFYY DYNTVQTVGMTLATILFLLG ILIVISKKVKCRKADSRSES PTCKSCKSELPSSAPGGGGV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human FXYD7 (NP_071289.1). |
Additional Info
| Post Translational Modifications | O-glycosylated.required for stabilization and translocation to the plasma membrane. |
| Function | Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Reduces the apparent affinity for external K(+), an effect that depends on the presence of external Na(+) and voltage. Increases the apparent affinity for intracellular Na(+). |
| Protein Name | Fxyd Domain-Containing Ion Transport Regulator 7 |
| Database Links | Reactome: R-HSA-5578775Reactome: R-HSA-936837Reactome: R-HSA-9679191 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinAble To Translocate To The Plasma Membrane Independent Of Its Association With Nka (In Vitro) |
| Alternative Antibody Names | Anti-Fxyd Domain-Containing Ion Transport Regulator 7 antibodyAnti-FXYD7 antibody |
Information sourced from Uniprot.org