Anti-FXYD7 antibody (1-80) (STJ117095)

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STJ117095
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FXYD7
Gene ID: 53822
Uniprot ID: FXYD7_HUMAN
Immunogen Region: 1-80
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human FXYD7 (NP_071289.1).
Immunogen Sequence: MATPTQTPTKAPEEPDPFYY DYNTVQTVGMTLATILFLLG ILIVISKKVKCRKADSRSES PTCKSCKSELPSSAPGGGGV
Post Translational Modifications O-glycosylated.required for stabilization and translocation to the plasma membrane.
Function Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Reduces the apparent affinity for external K(+), an effect that depends on the presence of external Na(+) and voltage. Increases the apparent affinity for intracellular Na(+).
Protein Name Fxyd Domain-Containing Ion Transport Regulator 7
Database Links Reactome: R-HSA-5578775
Reactome: R-HSA-936837
Reactome: R-HSA-9679191
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Able To Translocate To The Plasma Membrane Independent Of Its Association With Nka (In Vitro)
Alternative Antibody Names Anti-Fxyd Domain-Containing Ion Transport Regulator 7 antibody
Anti-FXYD7 antibody

Information sourced from Uniprot.org