| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FXYD7 |
| Gene ID: |
53822 |
| Uniprot ID: |
FXYD7_HUMAN |
| Immunogen Region: |
1-80 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human FXYD7 (NP_071289.1). |
| Immunogen Sequence: |
MATPTQTPTKAPEEPDPFYY DYNTVQTVGMTLATILFLLG ILIVISKKVKCRKADSRSES PTCKSCKSELPSSAPGGGGV |
| Post Translational Modifications | O-glycosylated.required for stabilization and translocation to the plasma membrane. |
| Function | Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Reduces the apparent affinity for external K(+), an effect that depends on the presence of external Na(+) and voltage. Increases the apparent affinity for intracellular Na(+). |
| Protein Name | Fxyd Domain-Containing Ion Transport Regulator 7 |
| Database Links | Reactome: R-HSA-5578775Reactome: R-HSA-936837Reactome: R-HSA-9679191 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinAble To Translocate To The Plasma Membrane Independent Of Its Association With Nka (In Vitro) |
| Alternative Antibody Names | Anti-Fxyd Domain-Containing Ion Transport Regulator 7 antibodyAnti-FXYD7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
