| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-FUT2 (29-150) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FUT2 |
| Gene ID: |
2524 |
| Uniprot ID: |
FUT2_HUMAN |
| Immunogen Region: |
29-150 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 29-150 of human FUT2 (NP_001091107.1). |
| Immunogen Sequence: |
QQRLAKIQAMWELPVQIPVL ASTSKALGPSQLRGMWTINA IGRLGNQMGEYATLYALAKM NGRPAFIPAQMHSTLAPIFR ITLPVLHSATASRIPWQNYH LNDWMEEEYRHIPGEYVRFT GY |
| Tissue Specificity | Small intestine, colon and lung. |
| Function | Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose on both O- and N-linked glycans chains of cell surface glycoproteins and glycolipids and the resulting epitope regulates several processes such as cell-cell interaction including host-microbe interaction, cell surface expression and cell proliferation. Preferentially fucosylates gangliosides GA1 and GM1 in the antrum, cecum and colon and in the female reproductive organs. Fucosylated host glycoproteins or glycolipids mediate interaction with intestinal microbiota influencing its composition. Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble ABO blood group antigen synthesis pathway. |
| Protein Name | Galactoside Alpha-(1 -2-Fucosyltransferase 2Alpha(1 -2ft 2Fucosyltransferase 2Gdp-L-Fucose -Beta-D-Galactoside 2-Alpha-L-Fucosyltransferase 2Se2Secretor Blood Group Alpha-2-FucosyltransferaseSecretor FactorSeType 1 Galactoside Alpha-(1 -2-Fucosyltransferase Fut2Type 2 Galactoside Alpha-(1 -2-Fucosyltransferase Fut2 |
| Database Links | Reactome: R-HSA-9033807Reactome: R-HSA-9037629 |
| Cellular Localisation | Golgi ApparatusGolgi Stack MembraneSingle-Pass Type Ii Membrane ProteinMembrane-Bound Form In Trans Cisternae Of Golgi |
| Alternative Antibody Names | Anti-Galactoside Alpha-(1 -2-Fucosyltransferase 2 antibodyAnti-Alpha(1 -2ft 2 antibodyAnti-Fucosyltransferase 2 antibodyAnti-Gdp-L-Fucose -Beta-D-Galactoside 2-Alpha-L-Fucosyltransferase 2 antibodyAnti-Se2 antibodyAnti-Secretor Blood Group Alpha-2-Fucosyltransferase antibodyAnti-Secretor Factor antibodyAnti-Se antibodyAnti-Type 1 Galactoside Alpha-(1 -2-Fucosyltransferase Fut2 antibodyAnti-Type 2 Galactoside Alpha-(1 -2-Fucosyltransferase Fut2 antibodyAnti-FUT2 antibodyAnti-SEC2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
