Anti-FTH1 antibody (C-Term) (STJ71797)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-FTH1 (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:2000.WB: Approx 20kDa band observed in Human Placenta lysates (calculated MW of 21.2kDa according to NP_002023.2). Recommended concentration: 0.3-1µg/ml. Primary incubation was 1 hour.IHC: |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | FTH1 |
| Gene ID | 2495 |
| Uniprot ID | FRIH_HUMAN |
| Accession Number | NP_002023.2 |
| Immunogen Region | C-Term |
| Immunogen Sequence | DKHTLGDSDNES |
Additional Info
| Function | Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. Delivery to lysosomes is mediated by the cargo receptor NCOA4 for autophagic degradation and release of iron. |
| Protein Name | Ferritin Heavy ChainFerritin H SubunitCell Proliferation-Inducing Gene 15 Protein Cleaved Into - Ferritin Heavy Chain - N-Terminally Processed |
| Database Links | Reactome: R-HSA-3000480Reactome: R-HSA-432722Reactome: R-HSA-6798695Reactome: R-HSA-917937 |
| Cellular Localisation | CytoplasmLysosomeCytoplasmic VesicleAutophagosome |
| Alternative Antibody Names | Anti-Ferritin Heavy Chain antibodyAnti-Ferritin H Subunit antibodyAnti-Cell Proliferation-Inducing Gene 15 Protein Cleaved Into - Ferritin Heavy Chain - N-Terminally Processed antibodyAnti-FTH1 antibodyAnti-FTH antibodyAnti-FTHL6 antibodyAnti-OK antibodyAnti-SW-cl.84 antibodyAnti-PIG15 antibody |
Information sourced from Uniprot.org