• STJ70388 (2µg/ml) staining of paraffin embedded Human Thyroid Gland. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.

Anti-FOXE1/TTF2 antibody (C-Term) (STJ70388)

SKU:
STJ70388-100

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Host: Goat
Applications: Pep-ELISA/IHC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-FOXE1/TTF2 (C-Term) is suitable for use in ELISA and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: IHC-2-4µg/ml, 5µg/ml
ELISA-antibody detection limit dilution 1:8000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: FOXE1
Gene ID: 2304
Uniprot ID: FOXE1_HUMAN
Immunogen Region: C-Term
Accession Number: NP_004464.2
Immunogen Sequence: AYPGGIDRFVSAM
Post Translational Modifications Phosphorylated.
Function Transcription factor that binds consensus sites on a variety of gene promoters and activate their transcription. Involved in proper palate formation, most probably through the expression of MSX1 and TGFB3 genes which are direct targets of this transcription factor. Also implicated in thyroid gland morphogenesis. May indirectly play a role in cell growth and migration through the regulation of WNT5A expression.
Protein Name Forkhead Box Protein E1
Forkhead Box Protein E2
Forkhead-Related Protein Fkhl15
Hfkh4
Hnf-3/Fork Head-Like Protein 5
Hfkl5
Thyroid Transcription Factor 2
Ttf-2
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Forkhead Box Protein E1 antibody
Anti-Forkhead Box Protein E2 antibody
Anti-Forkhead-Related Protein Fkhl15 antibody
Anti-Hfkh4 antibody
Anti-Hnf-3/Fork Head-Like Protein 5 antibody
Anti-Hfkl5 antibody
Anti-Thyroid Transcription Factor 2 antibody
Anti-Ttf-2 antibody
Anti-FOXE1 antibody
Anti-FKHL15 antibody
Anti-FOXE2 antibody
Anti-TITF2 antibody
Anti-TTF2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance