Anti-FOXE1/TTF2 antibody (C-Term) (STJ70388)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-FOXE1/TTF2 (C-Term) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/IHC |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:8000.WB: Preliminary experiments gave an approx 70kDa band in Human Thymus and Thyroid Gland lysates after 0.3µg/ml antibody staining. Please note that currently we cannot find an explanation in |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | FOXE1 |
| Gene ID | 2304 |
| Uniprot ID | FOXE1_HUMAN |
| Accession Number | NP_004464.2 |
| Immunogen Region | C-Term |
| Immunogen Sequence | AYPGGIDRFVSAM |
Additional Info
| Post Translational Modifications | Phosphorylated. |
| Function | Transcription factor that binds consensus sites on a variety of gene promoters and activate their transcription. Involved in proper palate formation, most probably through the expression of MSX1 and TGFB3 genes which are direct targets of this transcription factor. Also implicated in thyroid gland morphogenesis. May indirectly play a role in cell growth and migration through the regulation of WNT5A expression. |
| Protein Name | Forkhead Box Protein E1Forkhead Box Protein E2Forkhead-Related Protein Fkhl15Hfkh4Hnf-3/Fork Head-Like Protein 5Hfkl5Thyroid Transcription Factor 2Ttf-2 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Forkhead Box Protein E1 antibodyAnti-Forkhead Box Protein E2 antibodyAnti-Forkhead-Related Protein Fkhl15 antibodyAnti-Hfkh4 antibodyAnti-Hnf-3/Fork Head-Like Protein 5 antibodyAnti-Hfkl5 antibodyAnti-Thyroid Transcription Factor 2 antibodyAnti-Ttf-2 antibodyAnti-FOXE1 antibodyAnti-FKHL15 antibodyAnti-FOXE2 antibodyAnti-TITF2 antibodyAnti-TTF2 antibody |
Information sourced from Uniprot.org