Anti-FLOT1 antibody (128-427) (STJ11104576)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal Flotillin-1 (128-427) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FLOT1 |
| Gene ID | 10211 |
| Uniprot ID | FLOT1_HUMAN |
| Immunogen Region | 128-427 |
| Immunogen Sequence | SEQVFKVASSDLVNMGISVV SYTLKDIHDDQDYLHSLGKA RTAQVQKDARIGEAEAKRDA GIREAKAKQEKVSAQYLSEI EMAKAQRDYELKKAAYDIEV NTRRAQADLAYQLQVAKTKQ QIEEQRVQVQVVERAQQVAV QEQEIARREKELEARVRKPA EAERYKLERLAEAEKSQLIM QAEAEAASVRMRGEAEAFAI GARARAEAEQMAKKAEAFQL YQEAAQLDMLLEKLPQVAE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 128-427 of human Flotillin 1 (NP_005794.1). |
Additional Info
| Function | May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. |
| Protein Name | Flotillin-1 |
| Database Links | Reactome: R-HSA-5213460Reactome: R-HSA-5675482Reactome: R-HSA-8849932Reactome: R-HSA-8980692Reactome: R-HSA-9013026Reactome: R-HSA-9013106 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinEndosomeMembraneCaveolaMelanosomeMembrane RaftIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage IvMembrane-Associated Protein Of Caveola |
| Alternative Antibody Names | Anti-Flotillin-1 antibodyAnti-FLOT1 antibody |
Information sourced from Uniprot.org