Anti-FIP1L1 antibody (1-300) (STJ29218)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal FIP1L1 (1-300) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FIP1L1 |
| Gene ID | 81608 |
| Uniprot ID | FIP1_HUMAN |
| Immunogen Region | 1-300 |
| Immunogen Sequence | MSAGEVERLVSELSGGTGGD EEEEWLYGDENEVERPEEEN ASANPPSGIEDETAENGVPK PKVTETEDDSDSDSDDDEDD VHVTIGDIKTGAPQYGSYGT APVNLNIKTGGRVYGTTGTK VKGVDLDAPGSINGVPLLEV DLDSFEDKPWRKPGADLSDY FNYGFNEDTWKAYCEKQKRI RMGLEVIPVTSTTNKITAED CTMEVTPGAEIQDGRFNLFK VQQGRTGNSEKETALPSTK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human FIP1L1 (NP_001128409.1). |
Additional Info
| Function | Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A) polymerase to the CPSF complex. |
| Protein Name | Pre-Mrna 3'-End-Processing Factor Fip1Hfip1Fip1-Like 1 ProteinFactor Interacting With PapRearranged In Hypereosinophilia |
| Database Links | Reactome: R-HSA-159231Reactome: R-HSA-72187Reactome: R-HSA-72203Reactome: R-HSA-73856Reactome: R-HSA-77595Reactome: R-HSA-9673766 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Pre-Mrna 3'-End-Processing Factor Fip1 antibodyAnti-Hfip1 antibodyAnti-Fip1-Like 1 Protein antibodyAnti-Factor Interacting With Pap antibodyAnti-Rearranged In Hypereosinophilia antibodyAnti-FIP1L1 antibodyAnti-FIP1 antibodyAnti-RHE antibody |
Information sourced from Uniprot.org