Anti-FIGLA antibody (103-153 aa) (STJ195443)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human FIGLA at the amino acid range 103-153
General Information
| Short Description | Rabbit polyclonal anti-Factor in the germline alpha (103-153 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FIGLA |
| Gene ID | 344018 |
| Uniprot ID | FIGLA_HUMAN |
| Immunogen | Synthesized peptide derived from the human FIGLA at the amino acid range 103-153 |
| Immunogen Region | 103-153 aa |
| Specificity | This antibody detects endogenous levels of FIGLA at Human/Mouse |
Additional Info
| Function | Germline specific transcription factor implicated in postnatal oocyte-specific gene expression. Plays a key regulatory role in the expression of multiple oocyte-specific genes, including those that initiate folliculogenesis and those that encode the zona pellucida (ZP1, ZP2 and ZP3) required for fertilization and early embryonic survival. Essential for oocytes to survive and form primordial follicles. The persistence of FIGLA in adult females suggests that it may regulate additional pathways that are essential for normal ovarian development. Binds to the E-box (5'-CANNTG-3') of the ZPs (ZP1, ZP2, ZP3) promoters. |
| Protein Name | Factor In The Germline AlphaFigalphaClass C Basic Helix-Loop-Helix Protein 8Bhlhc8Folliculogenesis-Specific Basic Helix-Loop-Helix ProteinTranscription Factor Figa |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Factor In The Germline Alpha antibodyAnti-Figalpha antibodyAnti-Class C Basic Helix-Loop-Helix Protein 8 antibodyAnti-Bhlhc8 antibodyAnti-Folliculogenesis-Specific Basic Helix-Loop-Helix Protein antibodyAnti-Transcription Factor Figa antibodyAnti-FIGLA antibodyAnti-BHLHC8 antibody |
Information sourced from Uniprot.org