| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Factor in the germline alpha (103-153 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FIGLA |
| Gene ID: |
344018 |
| Uniprot ID: |
FIGLA_HUMAN |
| Immunogen Region: |
103-153 aa |
| Specificity: |
This antibody detects endogenous levels of FIGLA at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human FIGLA at the amino acid range 103-153 |
| Function | Germline specific transcription factor implicated in postnatal oocyte-specific gene expression. Plays a key regulatory role in the expression of multiple oocyte-specific genes, including those that initiate folliculogenesis and those that encode the zona pellucida (ZP1, ZP2 and ZP3) required for fertilization and early embryonic survival. Essential for oocytes to survive and form primordial follicles. The persistence of FIGLA in adult females suggests that it may regulate additional pathways that are essential for normal ovarian development. Binds to the E-box (5'-CANNTG-3') of the ZPs (ZP1, ZP2, ZP3) promoters. |
| Protein Name | Factor In The Germline AlphaFigalphaClass C Basic Helix-Loop-Helix Protein 8Bhlhc8Folliculogenesis-Specific Basic Helix-Loop-Helix ProteinTranscription Factor Figa |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Factor In The Germline Alpha antibodyAnti-Figalpha antibodyAnti-Class C Basic Helix-Loop-Helix Protein 8 antibodyAnti-Bhlhc8 antibodyAnti-Folliculogenesis-Specific Basic Helix-Loop-Helix Protein antibodyAnti-Transcription Factor Figa antibodyAnti-FIGLA antibodyAnti-BHLHC8 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
