Anti-FHL2 antibody (1-279aa) [AT21D11] (STJA0041859)

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STJA0041859
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Short Description :Mouse monoclonal anti-FHL2 (1-279aa) for use in ELISA, WB, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:ELISA/WB/ICC/IF
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :AT21D11
Isotype:IgG1k
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:By protein-A affinity chromatography
Formulation:Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:FHL2
Gene ID:2274
Uniprot ID:FHL2_HUMAN
Accession Number:NP_001034581
Immunogen:Recombinant human FHL2 (1-279aa) purified from E. coli.
Immunogen Region:1-279aa
Tissue Specificity Expressed in skeletal muscle and heart.
Function May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation. Negatively regulates the calcineurin/NFAT signaling pathway in cardiomyocytes.
Protein Name Four And A Half Lim Domains Protein 2
Fhl-2
Lim Domain Protein Dral
Skeletal Muscle Lim-Protein 3
Slim-3
Database Links Reactome: R-HSA-1989781
Cellular Localisation Cytoplasm
Nucleus
Myofibril
Sarcomere
Z Line
Alternative Antibody Names Anti-Four And A Half Lim Domains Protein 2 antibody
Anti-Fhl-2 antibody
Anti-Lim Domain Protein Dral antibody
Anti-Skeletal Muscle Lim-Protein 3 antibody
Anti-Slim-3 antibody
Anti-FHL2 antibody
Anti-DRAL antibody
Anti-SLIM3 antibody

Information sourced from Uniprot.org