Anti-FGL1/Hepassocin antibody (Internal) (STJ72036)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-FGL1/Hepassocin (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 35kDa band observed in Human Liver lysates (calculated MW of 36.4kDa according to NP_004458.3). Recommended concentration: 0.1-0.3µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | FGL1 |
| Gene ID | 2267 |
| Uniprot ID | FGL1_HUMAN |
| Accession Number | NP_004458.3 |
| Immunogen Region | Internal |
| Immunogen Sequence | ETRVKQQQVKIKQ |
| Specificity | Reported variants represent identical protein: NP_963846.1, NP_963847.1, NP_671736.2, NP_004458.3 |
Additional Info
| Function | Immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3. Responsible for LAG3 T-cell inhibitory function. Binds LAG3 independently from MHC class II (MHC-II). Secreted by, and promotes growth of, hepatocytes. |
| Protein Name | Fibrinogen-Like Protein 1Hp-041HepassocinHpsHepatocyte-Derived Fibrinogen-Related Protein 1Hfrep-1Liver Fibrinogen-Related Protein 1Lfire-1 |
| Cellular Localisation | SecretedSecreted In The Blood Plasma |
| Alternative Antibody Names | Anti-Fibrinogen-Like Protein 1 antibodyAnti-Hp-041 antibodyAnti-Hepassocin antibodyAnti-Hps antibodyAnti-Hepatocyte-Derived Fibrinogen-Related Protein 1 antibodyAnti-Hfrep-1 antibodyAnti-Liver Fibrinogen-Related Protein 1 antibodyAnti-Lfire-1 antibodyAnti-FGL1 antibodyAnti-HFREP1 antibody |
Information sourced from Uniprot.org