| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Mouse/Rat/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-FGL1/Hepassocin (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 35kDa band observed in Human Liver lysates (calculated MW of 36.4kDa according to NP_004458.3). Recommended concentration: 0.1-0.3µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | FGL1 |
| Gene ID: | 2267 |
| Uniprot ID: | FGL1_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_004458.3 |
| Specificity: | Reported variants represent identical protein: NP_963846.1, NP_963847.1, NP_671736.2, NP_004458.3 |
| Immunogen Sequence: | ETRVKQQQVKIKQ |
| Function | Immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3. Responsible for LAG3 T-cell inhibitory function. Binds LAG3 independently from MHC class II (MHC-II). Secreted by, and promotes growth of, hepatocytes. |
| Protein Name | Fibrinogen-Like Protein 1Hp-041HepassocinHpsHepatocyte-Derived Fibrinogen-Related Protein 1Hfrep-1Liver Fibrinogen-Related Protein 1Lfire-1 |
| Cellular Localisation | SecretedSecreted In The Blood Plasma |
| Alternative Antibody Names | Anti-Fibrinogen-Like Protein 1 antibodyAnti-Hp-041 antibodyAnti-Hepassocin antibodyAnti-Hps antibodyAnti-Hepatocyte-Derived Fibrinogen-Related Protein 1 antibodyAnti-Hfrep-1 antibodyAnti-Liver Fibrinogen-Related Protein 1 antibodyAnti-Lfire-1 antibodyAnti-FGL1 antibodyAnti-HFREP1 antibody |
Information sourced from Uniprot.org