Anti-FGL1 antibody (Full Length) [S3965RM] (STJ11103965)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Fibrinogen-Like Protein 1 (Full Length) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S3965RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FGL1 |
| Gene ID | 2267 |
| Uniprot ID | FGL1_HUMAN |
| Immunogen Region | Full Length |
| Immunogen Sequence | MAKVFSFILVTTALTMGREI SALEDCAQEQMRLRAQVRLL ETRVKQQQVKIKQLLQENEV QFLDKGDENTVIDLGSKRQY ADCSEIFNDGYKLSGFYKIK PLQSPAEFSVYCDMSDGGGW TVIQRRSDGSENFNRGWKDY ENGFGNFVQKHGEYWLGNKN LHFLTTQEDYTLKIDLADFE KNSRYAQYKNFKVGDEKNFY ELNIGEYSGTAGDSLAGNFH PEVQWWASHQRMKFSTWDR |
| Specificity | Recombinant protein of human FGL-1 Full length (NP_004458.3). |
Additional Info
| Tissue Specificity | Under normal conditions, liver-specific. |
| Function | Immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3. Responsible for LAG3 T-cell inhibitory function. Binds LAG3 independently from MHC class II (MHC-II). Secreted by, and promotes growth of, hepatocytes. |
| Protein Name | Fibrinogen-Like Protein 1Hp-041HepassocinHpsHepatocyte-Derived Fibrinogen-Related Protein 1Hfrep-1Liver Fibrinogen-Related Protein 1Lfire-1 |
| Database Links | |
| Cellular Localisation | SecretedSecreted In The Blood Plasma |
| Alternative Antibody Names | Anti-Fibrinogen-Like Protein 1 antibodyAnti-Hp-041 antibodyAnti-Hepassocin antibodyAnti-Hps antibodyAnti-Hepatocyte-Derived Fibrinogen-Related Protein 1 antibodyAnti-Hfrep-1 antibodyAnti-Liver Fibrinogen-Related Protein 1 antibodyAnti-Lfire-1 antibodyAnti-FGL1 antibodyAnti-HFREP1 antibody |
Information sourced from Uniprot.org