| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-FGFBP1 (24-234) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FGFBP1 |
| Gene ID: |
9982 |
| Uniprot ID: |
FGFP1_HUMAN |
| Immunogen Region: |
24-234 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 24-234 of human FGFBP1 (NP_005121.1). |
| Immunogen Sequence: |
KKKVKNGLHSKVVSEQKDTL GNTQIKQKSRPGNKGKFVTK DQANCRWAATEQEEGISLKV ECTQLDHEFSCVFAGNPTSC LKLKDERVYWKQVARNLRSQ KDICRYSKTAVKTRVCRKDF PESSLKLVSSTLFGNTKPRK EKTEMSPREHIKGKETTPSS LAVTQTMATKAPECVEDPDM ANQRKTALEFCGETWSSLCT FFLSIVQDTSC |
| Tissue Specificity | Expressed in the suprabasal region of the epidermis, in hair follicles, the basement membrane at the dermo-epidermal junction (occasionally extending into the basement membrane of dermal blood vessels), wounded skin and several invasive squamous cell carcinomas (at protein level). Expressed in normal and wounded skin and various squamous cell carcinomas. |
| Function | Acts as a carrier protein that release fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth. |
| Protein Name | Fibroblast Growth Factor-Binding Protein 1Fgf-BpFgf-Bp1Fgf-Binding Protein 1Fgfbp-117 Kda Heparin-Binding Growth Factor-Binding Protein17 Kda Hbgf-Binding ProteinHbp17 |
| Database Links | Reactome: R-HSA-190377 |
| Cellular Localisation | SecretedExtracellular SpaceCell MembranePeripheral Membrane ProteinExtracellular And Plasma Membrane-AssociatedColocalizes With Hspg2 In The Pericellular Environment Of Squamous Cell Carcinomas |
| Alternative Antibody Names | Anti-Fibroblast Growth Factor-Binding Protein 1 antibodyAnti-Fgf-Bp antibodyAnti-Fgf-Bp1 antibodyAnti-Fgf-Binding Protein 1 antibodyAnti-Fgfbp-1 antibodyAnti-17 Kda Heparin-Binding Growth Factor-Binding Protein antibodyAnti-17 Kda Hbgf-Binding Protein antibodyAnti-Hbp17 antibodyAnti-FGFBP1 antibodyAnti-FGFBP antibodyAnti-HBP17 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
