Anti-FGFBP1 antibody (24-234) (STJ29594)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal FGFBP1 (24-234) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FGFBP1 |
| Gene ID | 9982 |
| Uniprot ID | FGFP1_HUMAN |
| Immunogen Region | 24-234 |
| Immunogen Sequence | KKKVKNGLHSKVVSEQKDTL GNTQIKQKSRPGNKGKFVTK DQANCRWAATEQEEGISLKV ECTQLDHEFSCVFAGNPTSC LKLKDERVYWKQVARNLRSQ KDICRYSKTAVKTRVCRKDF PESSLKLVSSTLFGNTKPRK EKTEMSPREHIKGKETTPSS LAVTQTMATKAPECVEDPDM ANQRKTALEFCGETWSSLCT FFLSIVQDTSC |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 24-234 of human FGFBP1 (NP_005121.1). |
Additional Info
| Tissue Specificity | Expressed in the suprabasal region of the epidermis, in hair follicles, the basement membrane at the dermo-epidermal junction (occasionally extending into the basement membrane of dermal blood vessels), wounded skin and several invasive squamous cell carcinomas (at protein level). Expressed in normal and wounded skin and various squamous cell carcinomas. |
| Function | Acts as a carrier protein that release fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth. |
| Protein Name | Fibroblast Growth Factor-Binding Protein 1Fgf-BpFgf-Bp1Fgf-Binding Protein 1Fgfbp-117 Kda Heparin-Binding Growth Factor-Binding Protein17 Kda Hbgf-Binding ProteinHbp17 |
| Database Links | Reactome: R-HSA-190377 |
| Cellular Localisation | SecretedExtracellular SpaceCell MembranePeripheral Membrane ProteinExtracellular And Plasma Membrane-AssociatedColocalizes With Hspg2 In The Pericellular Environment Of Squamous Cell Carcinomas |
| Alternative Antibody Names | Anti-Fibroblast Growth Factor-Binding Protein 1 antibodyAnti-Fgf-Bp antibodyAnti-Fgf-Bp1 antibodyAnti-Fgf-Binding Protein 1 antibodyAnti-Fgfbp-1 antibodyAnti-17 Kda Heparin-Binding Growth Factor-Binding Protein antibodyAnti-17 Kda Hbgf-Binding Protein antibodyAnti-Hbp17 antibodyAnti-FGFBP1 antibodyAnti-FGFBP antibodyAnti-HBP17 antibody |
Information sourced from Uniprot.org