• Western blot analysis of extracts of various cell lines, using FGF13 antibody (STJ110204) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
  • Western blot analysis of extracts of various cell lines, using FGF13 antibody (STJ110204) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-FGF13 antibody (1-245) (STJ110204)

SKU:
STJ110204

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-FGF13 (1-245) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FGF13
Gene ID: 2258
Uniprot ID: FGF13_HUMAN
Immunogen Region: 1-245
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human FGF13 (NP_004105.1).
Immunogen Sequence: MAAAIASSLIRQKRQARERE KSNACKCVSSPSKGKTSCDK NKLNVFSRVKLFGSKKRRRR RPEPQLKGIVTKLYSRQGYH LQLQADGTIDGTKDEDSTYT LFNLIPVGLRVVAIQGVQTK LYLAMNSEGYLYTSELFTPE CKFKESVFENYYVTYSSMIY RQQQSGRGWYLGLNKEGEIM KGNHVKKNKPAAHFLPKPLK VAMYKEPSLHDLTEFSRSGS GTPTKSRSVSGVLNGGKSM
Tissue Specificity Ubiquitously expressed. Predominantly expressed in the nervous system.
Post Translational Modifications May be phosphorylated.
Function Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. Regulates voltage-gated sodium channel transport and function. May also play a role in MAPK signaling. Required for the development of axonal initial segment-targeting inhibitory GABAergic synapses made by chandelier neurons.
Protein Name Fibroblast Growth Factor 13
Fgf-13
Fibroblast Growth Factor Homologous Factor 2
Fhf-2
Database Links Reactome: R-HSA-5576892
Cellular Localisation Isoform 1: Nucleus
Isoform 2: Cytoplasm
Nucleus
Isoform 3: Cytoplasm
Isoform 4: Cytoplasm
Isoform 5: Cytoplasm
Cell Projection
Filopodium
Growth Cone
Dendrite
Cell Membrane
Sarcolemma
Cytoplasm
Not Secreted
Localizes To The Lateral Membrane And Intercalated Disks Of Myocytes
Alternative Antibody Names Anti-Fibroblast Growth Factor 13 antibody
Anti-Fgf-13 antibody
Anti-Fibroblast Growth Factor Homologous Factor 2 antibody
Anti-Fhf-2 antibody
Anti-FGF13 antibody
Anti-FHF2 antibody

Information sourced from Uniprot.org

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