Anti-FBLN5 antibody [3F10A5/3F8A12] (STJ98074)

SKU:
STJ98074
£149.00 - £360.00
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Short Description :Mouse monoclonal anti-Fibulin-5 for use in WB, IHC, IF and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC/IF/ELISA
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :3F10A5/3F8A12
Isotype:IgG1
Conjugation:Unconjugated
Purification:Affinity purification
Dilution Range:WB 1:500-1:2000
IHC 1:200-1:1000
ELISA 1:10000
IF 1:50-200
Formulation:Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:FBLN5
Gene ID:10516
Uniprot ID:FBLN5_HUMAN
Immunogen:Purified recombinant fragment of Fibulin-5 expressed in E. Coli.
Specificity:Fibulin-5 Monoclonal Antibody detects endogenous levels of Fibulin-5 protein.
Post Translational Modifications N-glycosylated.
Function Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN. Stabilizes and organizes elastic fibers in the skin, lung and vasculature. Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling. May act as an adapter that mediates the interaction between FBN1 and ELN.
Protein Name Fibulin-5
Fibl-5
Developmental Arteries And Neural Crest Egf-Like Protein
Dance
Urine P50 Protein
Up50
Database Links Reactome: R-HSA-1566948
Reactome: R-HSA-2129379
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Co-Localizes With Eln In Elastic Fibers
Alternative Antibody Names Anti-Fibulin-5 antibody
Anti-Fibl-5 antibody
Anti-Developmental Arteries And Neural Crest Egf-Like Protein antibody
Anti-Dance antibody
Anti-Urine P50 Protein antibody
Anti-Up50 antibody
Anti-FBLN5 antibody
Anti-DANCE antibody
Anti-UNQ184 antibody
Anti-PRO210 antibody

Information sourced from Uniprot.org