Anti-FBLN5 antibody [3F10A5/3F8A12] (STJ98074)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenPurified recombinant fragment of Fibulin-5 expressed in E. Coli.
General Information
| Short Description | Mouse monoclonal anti-Fibulin-5 for use in WB, IHC, IF and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 3F10A5/3F8A12 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB 1:500-1:2000IHC 1:200-1:1000ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FBLN5 |
| Gene ID | 10516 |
| Uniprot ID | FBLN5_HUMAN |
| Immunogen | Purified recombinant fragment of Fibulin-5 expressed in E. Coli. |
| Specificity | Fibulin-5 Monoclonal Antibody detects endogenous levels of Fibulin-5 protein. |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN. Stabilizes and organizes elastic fibers in the skin, lung and vasculature. Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling. May act as an adapter that mediates the interaction between FBN1 and ELN. |
| Protein Name | Fibulin-5Fibl-5Developmental Arteries And Neural Crest Egf-Like ProteinDanceUrine P50 ProteinUp50 |
| Database Links | Reactome: R-HSA-1566948Reactome: R-HSA-2129379 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixCo-Localizes With Eln In Elastic Fibers |
| Alternative Antibody Names | Anti-Fibulin-5 antibodyAnti-Fibl-5 antibodyAnti-Developmental Arteries And Neural Crest Egf-Like Protein antibodyAnti-Dance antibodyAnti-Urine P50 Protein antibodyAnti-Up50 antibodyAnti-FBLN5 antibodyAnti-DANCE antibodyAnti-UNQ184 antibodyAnti-PRO210 antibody |
Information sourced from Uniprot.org