• Immunohistochemistry analysis of F4/80 in paraffin-embedded mouse spleen using F4/80 Rabbit monoclonal antibody (STJ11105223) at dilution of 1:200 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of F4/80 in paraffin-embedded mouse liver using F4/80 Rabbit monoclonal antibody (STJ11105223) at dilution of 1:200 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of F4/80 in paraffin-embedded mouse colon using F4/80 Rabbit monoclonal antibody (STJ11105223) at dilution of 1:200 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.

Anti-F4/80 antibody (367-645) [S5223RM] (STJ11105223)

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STJ11105223

€183.13 - €799.38
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Host: Rabbit
Applications: IHC
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-F4/80 (367-645) is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: S5223RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: Adgre1
Gene ID: 13733
Uniprot ID: AGRE1_MOUSE
Immunogen Region: 367-645
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 367-645 of mouse F4/80 (NP_034260.1).
Immunogen Sequence: KRILFKCKEDLILQSEQIQQ CQAVQGRDLGYASFCTLVNA TFTILDNTCENKSAPVSLQS AATSVSLVLEQATTWFELSK EETSTLGTILLETVESTMLA ALLIPSGNASQMIQTEYLDI ESKVINEECKENESINLAAR GDKMNVGCFIIKESVSTGAP GVAFVSFAHMESVLNERFFE DGQSFRKLRMNSRVVGGTVT GEKKEDFSKPIIYTLQHIQP KQKSERPICVSWNTDVEDG
Tissue Specificity In macrophages.but absent from those which are localized within T-cell areas of lymph nodes and spleen. Low level of expression on blood monocytes.
Function Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development.
Protein Name Adhesion G Protein-Coupled Receptor E1
Cell Surface Glycoprotein F4/80
Egf-Like Module Receptor 1
Egf-Like Module-Containing Mucin-Like Hormone Receptor-Like 1
Emr1 Hormone Receptor
Database Links Reactome: R-MMU-373080
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Adhesion G Protein-Coupled Receptor E1 antibody
Anti-Cell Surface Glycoprotein F4/80 antibody
Anti-Egf-Like Module Receptor 1 antibody
Anti-Egf-Like Module-Containing Mucin-Like Hormone Receptor-Like 1 antibody
Anti-Emr1 Hormone Receptor antibody
Anti-Adgre1 antibody
Anti-Emr1 antibody
Anti-Gpf480 antibody

Information sourced from Uniprot.org

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