Anti-F4/80 antibody (367-645) [S5223RM] (STJ11105223)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal F4/80 (367-645) antibody for use in IHC-P and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S5223RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | Adgre1 |
| Gene ID | 13733 |
| Uniprot ID | AGRE1_MOUSE |
| Immunogen Region | 367-645 |
| Immunogen Sequence | KRILFKCKEDLILQSEQIQQ CQAVQGRDLGYASFCTLVNA TFTILDNTCENKSAPVSLQS AATSVSLVLEQATTWFELSK EETSTLGTILLETVESTMLA ALLIPSGNASQMIQTEYLDI ESKVINEECKENESINLAAR GDKMNVGCFIIKESVSTGAP GVAFVSFAHMESVLNERFFE DGQSFRKLRMNSRVVGGTVT GEKKEDFSKPIIYTLQHIQP KQKSERPICVSWNTDVEDG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 367-645 of mouse F4/80 (NP_034260.1). |
Additional Info
| Tissue Specificity | In macrophages.but absent from those which are localized within T-cell areas of lymph nodes and spleen. Low level of expression on blood monocytes. |
| Function | Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development. |
| Protein Name | Adhesion G Protein-Coupled Receptor E1Cell Surface Glycoprotein F4/80Egf-Like Module Receptor 1Egf-Like Module-Containing Mucin-Like Hormone Receptor-Like 1Emr1 Hormone Receptor |
| Database Links | Reactome: R-MMU-373080 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Adhesion G Protein-Coupled Receptor E1 antibodyAnti-Cell Surface Glycoprotein F4/80 antibodyAnti-Egf-Like Module Receptor 1 antibodyAnti-Egf-Like Module-Containing Mucin-Like Hormone Receptor-Like 1 antibodyAnti-Emr1 Hormone Receptor antibodyAnti-Adgre1 antibodyAnti-Emr1 antibodyAnti-Gpf480 antibody |
Information sourced from Uniprot.org