Anti-EXOC7 antibody (Internal) (STJ70915)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-EXOC7 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Pig/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 70kDa band observed in Human Lung lysates (calculated MW of 74.7kDa according to NP_056034.2). Recommended concentration: 0.5-1.5µg/ml.IHC: In paraffin embedded Human Adren |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | EXOC7 |
| Gene ID | 23265 |
| Uniprot ID | EXOC7_HUMAN |
| Accession Number | NP_001013861.1; NP_056034.2; NP_001138769.1; NP_001138771.1; NP_001138770.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | DNIKNDPDKEYN |
| Specificity | This antibody is expected to recognise all five reported isoforms (NP_001013861.1; NP_056034.2; NP_001138769.1; NP_001138771.1; NP_001138770.1). |
Additional Info
| Function | Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion. It is required for neuron survival and plays an essential role in cortical development. |
| Protein Name | Exocyst Complex Component 7Exocyst Complex Component Exo70 |
| Database Links | Reactome: R-HSA-1445148Reactome: R-HSA-264876Reactome: R-HSA-5620916 |
| Cellular Localisation | CytoplasmCytosolCell MembranePeripheral Membrane ProteinMidbodyMidbody RingTranslocatesAs A Preformed Complex With Exoc3/Sec6 And Exoc4/Sec8To The Plasma Membrane In Response To Insulin Through The Activation Of ArhqColocalizes With Cntrl/Centriolin At The Midbody Ring |
| Alternative Antibody Names | Anti-Exocyst Complex Component 7 antibodyAnti-Exocyst Complex Component Exo70 antibodyAnti-EXOC7 antibodyAnti-EXO70 antibodyAnti-KIAA1067 antibody |
Information sourced from Uniprot.org