Anti-Estrogen Inducible Protein pS2 antibody [6G1-7C8-9B6] (STJA0033532)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
ImmunogenSynthesized peptide derived from human pS2
General Information
| Short Description | Mouse monoclonal anti-Estrogen Inducible Protein pS2 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 6G1-7C8-9B6 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Dilution Range | IHC 1:100-1:500 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | TFF1 |
| Gene ID | 7031 |
| Uniprot ID | TFF1_HUMAN |
| Immunogen | Synthesized peptide derived from human pS2 |
Additional Info
| Tissue Specificity | Found in stomach, with highest levels in the upper gastric mucosal cells (at protein level). Detected in goblet cells of the small and large intestine and rectum, small submucosal glands in the esophagus, mucous acini of the sublingual gland, submucosal glands of the trachea, and epithelial cells lining the exocrine pancreatic ducts but not in the remainder of the pancreas (at protein level). Scattered expression is detected in the epithelial cells of the gallbladder and submucosal glands of the vagina, and weak expression is observed in the bronchial goblet cells of the pseudostratified epithelia in the respiratory system (at protein level). Detected in urine (at protein level). Strongly expressed in breast cancer but at low levels in normal mammary tissue. It is regulated by estrogen in MCF-7 cells. Strong expression found in normal gastric mucosa and in the regenerative tissues surrounding ulcerous lesions of gastrointestinal tract, but lower expression found in gastric cancer (at protein level). |
| Function | Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine. |
| Protein Name | Trefoil Factor 1Breast Cancer Estrogen-Inducible ProteinPnr-2Polypeptide P1.AHp1.AProtein Ps2 |
| Database Links | Reactome: R-HSA-9018519 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Trefoil Factor 1 antibodyAnti-Breast Cancer Estrogen-Inducible Protein antibodyAnti-Pnr-2 antibodyAnti-Polypeptide P1.A antibodyAnti-Hp1.A antibodyAnti-Protein Ps2 antibodyAnti-TFF1 antibodyAnti-BCEI antibodyAnti-PS2 antibody |
Information sourced from Uniprot.org