• STJ71481 (0. 2µg/ml) staining of Human Breast lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • HEK293 overexpressing ESRRG (RC218233) and probed with STJ71481 (mock transfection in first lane) , tested by Origene.

Anti-ESRRG antibody (Internal) (STJ71481)

SKU:
STJ71481-100

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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human/Mouse/Dog
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-ESRRG (Internal) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: ELISA-antibody detection limit dilution 1:16000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: ESRRG
Gene ID: 2104
Uniprot ID: ERR3_HUMAN
Immunogen Region: Internal
Accession Number: NP_001429.2; NP_996317.1; NP_996318.1
Specificity: This antibody is expected to recognise the reported isoform NP_001429.2.
Immunogen Sequence: CRMSNKDRHIDS
Post Translational Modifications Acetylated by PCAF/KAT2 (in vitro). Sumoylation on Lys-40 is enhanced by phosphorylation at Ser-45 and represses transcriptional activity. Phosphorylation on Ser-45 enhances sumoylation on Lys-40 thus repressing transcriptional activity.
Function Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements. Induces the expression of PERM1 in the skeletal muscle.
Protein Name Estrogen-Related Receptor Gamma
Err Gamma-2
Estrogen Receptor-Related Protein 3
Nuclear Receptor Subfamily 3 Group B Member 3
Database Links Reactome: R-HSA-383280
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Estrogen-Related Receptor Gamma antibody
Anti-Err Gamma-2 antibody
Anti-Estrogen Receptor-Related Protein 3 antibody
Anti-Nuclear Receptor Subfamily 3 Group B Member 3 antibody
Anti-ESRRG antibody
Anti-ERR3 antibody
Anti-ERRG2 antibody
Anti-KIAA0832 antibody
Anti-NR3B3 antibody

Information sourced from Uniprot.org

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