Anti-ESRP2 antibody (STJ191810)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Epithelial splicing regulatory protein 2 for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ESRP2 |
| Gene ID | 80004 |
| Uniprot ID | ESRP2_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | ESRP2 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2. |
| Protein Name | Epithelial Splicing Regulatory Protein 2Rna-Binding Motif Protein 35bRna-Binding Protein 35b |
| Database Links | Reactome: R-HSA-6803529 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Epithelial Splicing Regulatory Protein 2 antibodyAnti-Rna-Binding Motif Protein 35b antibodyAnti-Rna-Binding Protein 35b antibodyAnti-ESRP2 antibodyAnti-RBM35B antibodyAnti-PP7059 antibody |
Information sourced from Uniprot.org