| Short Description : | Rabbit polyclonal anti-Epithelial splicing regulatory protein 2 for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ESRP2 |
| Gene ID: | 80004 |
| Uniprot ID: | ESRP2_HUMAN |
| Immunogen: | Synthesized peptide derived from part of the human protein |
| Specificity: | ESRP2 Polyclonal Antibody detects endogenous levels of protein. |
| Function | mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2. |
| Protein Name | Epithelial Splicing Regulatory Protein 2Rna-Binding Motif Protein 35bRna-Binding Protein 35b |
| Database Links | Reactome: R-HSA-6803529 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Epithelial Splicing Regulatory Protein 2 antibodyAnti-Rna-Binding Motif Protein 35b antibodyAnti-Rna-Binding Protein 35b antibodyAnti-ESRP2 antibodyAnti-RBM35B antibodyAnti-PP7059 antibody |
Information sourced from Uniprot.org
