Anti-ENDOU antibody (32-82 aa) (STJ197636)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human ENDOU at the amino acid range 32-82
General Information
| Short Description | Rabbit polyclonal anti-Uridylate-specific endoribonuclease (32-82 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ENDOU |
| Gene ID | 8909 |
| Uniprot ID | ENDOU_HUMAN |
| Immunogen | Synthesized peptide derived from the human ENDOU at the amino acid range 32-82 |
| Immunogen Region | 32-82 aa |
| Specificity | This antibody detects endogenous levels of human ENDOU |
Additional Info
| Post Translational Modifications | It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability, thus two alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both. |
| Function | Endoribonuclease that cleaves single-stranded RNAs at 5' of uridylates and releases a product with a 2',3'-cyclic phosphate at the 3'-end. The UU and GU sites are more efficiently cleaved than CU and AU sites. Targets mRNAs to regulate their expression. |
| Protein Name | Uridylate-Specific EndoribonucleasePlacental Protein 11Pp11Protein Endou |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Uridylate-Specific Endoribonuclease antibodyAnti-Placental Protein 11 antibodyAnti-Pp11 antibodyAnti-Protein Endou antibodyAnti-ENDOU antibody |
Information sourced from Uniprot.org