Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Uridylate-specific endoribonuclease (32-82 aa) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:1000-2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ENDOU |
Gene ID: |
8909 |
Uniprot ID: |
ENDOU_HUMAN |
Immunogen Region: |
32-82 aa |
Specificity: |
This antibody detects endogenous levels of human ENDOU |
Immunogen: |
Synthesized peptide derived from the human ENDOU at the amino acid range 32-82 |
Post Translational Modifications | It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability, thus two alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both. |
Function | Endoribonuclease that cleaves single-stranded RNAs at 5' of uridylates and releases a product with a 2',3'-cyclic phosphate at the 3'-end. The UU and GU sites are more efficiently cleaved than CU and AU sites. Targets mRNAs to regulate their expression. |
Protein Name | Uridylate-Specific EndoribonucleasePlacental Protein 11Pp11Protein Endou |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Uridylate-Specific Endoribonuclease antibodyAnti-Placental Protein 11 antibodyAnti-Pp11 antibodyAnti-Protein Endou antibodyAnti-ENDOU antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance