Anti-ENDOD1 antibody (22-330) (STJ118929)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ENDOD1 (22-330) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ENDOD1 |
| Gene ID | 23052 |
| Uniprot ID | ENDD1_HUMAN |
| Immunogen Region | 22-330 |
| Immunogen Sequence | RLVGEEEAGFGECDKFFYAG TPPAGLAADSHVKICQRAEG AERFATLYSTRDRIPVYSAF RAPRPAPGGAEQRWLVEPQI DDPNSNLEEAINEAEAITSV NSLGSKQALNTDYLDSDYQR GQLYPFSLSSDVQVATFTLT NSAPMTQSFQERWYVNLHSL MDRALTPQCGSGEDLYILTG TVPSDYRVKDKVAVPEFVWL AACCAVPGGGWAMGFVKHTR DSDIIEDVMVKDLQKLLPF |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 22-330 of human ENDOD1 (NP_055851.1). |
Additional Info
| Function | May act as a DNase and a RNase. Plays a role in the modulation of innate immune signaling through the cGAS-STING pathway by interacting with RNF26. |
| Protein Name | Endonuclease Domain-Containing 1 Protein |
| Database Links | Reactome: R-HSA-114608 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Endonuclease Domain-Containing 1 Protein antibodyAnti-ENDOD1 antibodyAnti-KIAA0830 antibody |
Information sourced from Uniprot.org