| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ENDOD1 (22-330) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ENDOD1 |
| Gene ID: |
23052 |
| Uniprot ID: |
ENDD1_HUMAN |
| Immunogen Region: |
22-330 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 22-330 of human ENDOD1 (NP_055851.1). |
| Immunogen Sequence: |
RLVGEEEAGFGECDKFFYAG TPPAGLAADSHVKICQRAEG AERFATLYSTRDRIPVYSAF RAPRPAPGGAEQRWLVEPQI DDPNSNLEEAINEAEAITSV NSLGSKQALNTDYLDSDYQR GQLYPFSLSSDVQVATFTLT NSAPMTQSFQERWYVNLHSL MDRALTPQCGSGEDLYILTG TVPSDYRVKDKVAVPEFVWL AACCAVPGGGWAMGFVKHTR DSDIIEDVMVKDLQKLLPF |
| Function | May act as a DNase and a RNase. Plays a role in the modulation of innate immune signaling through the cGAS-STING pathway by interacting with RNF26. |
| Protein Name | Endonuclease Domain-Containing 1 Protein |
| Database Links | Reactome: R-HSA-114608 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Endonuclease Domain-Containing 1 Protein antibodyAnti-ENDOD1 antibodyAnti-KIAA0830 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
