| Short Description : | Rabbit polyclonal anti-BRCA2-interacting transcriptional repressor EMSY for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EMSY |
| Gene ID: | 56946 |
| Uniprot ID: | EMSY_HUMAN |
| Immunogen: | Synthesized peptide derived from human C11orf30 |
| Specificity: | This antibody detects endogenous levels of C11orf30 at Human, Mouse |
| Function | Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2. Mediates ligand-dependent transcriptional activation by nuclear hormone receptors. |
| Protein Name | Brca2-Interacting Transcriptional Repressor Emsy |
| Database Links | |
| Cellular Localisation | NucleusLocalizes To Dna Damage Markers In Irradiated CellsSuggesting That It Participates In Dna Repair Process |
| Alternative Antibody Names | Anti-Brca2-Interacting Transcriptional Repressor Emsy antibodyAnti-EMSY antibodyAnti-C11orf30 antibodyAnti-GL002 antibody |
Information sourced from Uniprot.org
